DENAFINE-250 TABLETS
COMPOSITION
Terbinafine 250mg tablets
PACK SIZE
10*1*7
PACKING
Blister
THERAPEUTIC CATEGORY
Antifungal
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Uses
Onychomycosis: Terbinafine is commonly used to treat fungal infections of the toenails and fingernails.
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Tinea Infections: It is also effective in treating tinea infections, such as:
- Tinea Pedis(Athlete’s Foot)
- Tinea Cruris(Jock Itch)
- Tinea Corporis(Ringworm)
Effects on the Body
Antifungal Action: Terbinafine is an allylamine antifungal that works by inhibiting the enzyme squalene epoxidase. This enzyme is crucial for the synthesis of ergosterol, an essential component of fungal cell membranes. Inhibition of squalene epoxidase leads to an accumulation of squalene, which is toxic to fungi, and a deficiency of ergosterol, compromising the fungal cell membrane’s integrity and resulting in cell death.
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Fungicidal Effect: Terbinafine is fungicidal, meaning it kills the fungi causing the infection. This direct action helps in effectively clearing up the infection.
How to Use
Dosage: The usual recommended dose for adults is 250mg once daily. Always follow the specific instructions provided by your healthcare provider.
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Administration: Take the tablet with a full glass of water, with or without food.
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Duration: The duration of treatment depends on the type and severity of the infection. For nail infections, treatment typically lasts 6 weeks for fingernails and 12 weeks for toenails. For skin infections, the duration may range from 2 to 6 weeks. Always complete the full course of treatment as prescribed, even if symptoms improve before the medication is finished.
Precautions
Allergies: Inform your healthcare provider if you have any known allergies to terbinafine
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Pregnancy and Breastfeeding: Consult your healthcare provider before using terbinafine if you are pregnant or breastfeeding.
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Medical Conditions: Inform your healthcare provider if you have any pre-existing medical conditions, particularly liver or kidney diseases, as dosage adjustments may be necessary. Â
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Drug Interactions: Terbinafine can interact with a variety of medications, including certain antidepressants, beta-blockers, and other drugs. Inform your physician about all medications and supplements you are taking to avoid potential interactions.
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